The Pastoral Epistles (1 + 2 Timothy, Titus), unlike most of Paul’s other letters which were written to entire churches, provided doctrinal, organizational, and personal instruction for individuals involved in the daily grind of ministry.
When? - Not during Acts -Probably after the book of Acts when Paul has been released from prison, is contenting his mission work, and before his final imprisonment that leads to his execution. - AD62-65