Actemra
Published on Jun 28, 2017
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PRESENTATION OUTLINE
ACTEMRA
Failure to Warn
The FDA approved Roche/Genentechs Actemra to treat rheumatoid arthritis in 2010 and giant cell arteritis in May of 2017.
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Rheumatoid Arthritis affects about 1.5 million Americans
A STAT publication tells of hundreds of deaths from Actemra use. The manufacturer has not listed the dangers on the label.
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The overall rate of adverse events, serious infections, & confirmed gastrointestinal perforations was higher for Actemra vs. similar drugs.
Other drugs in this category like Humira and Remicade warn of these risks, Actemra does not.
Photo by sheila_blige
Common Side Effects
- Serious Infections
- Headache
- Dizziness
- Runny nose/sore throat
- Stomach cramps
- Itching
- Blood cholesterol increased
Life Threatening Effects
- Hypotension
- Gastrointestinal perforation
- Respiratory Failure
- Liver or kidney failure
- Drug reaction requiring Hospitalization
- Interstitial Lung Disease
- Death
Interstitial lung disease example: pneumonia or lung fibrosis/lung scarring.
Risks NOT listed on label
- Heart Attack
- Atrial Fibrillation
- Cardiac Arrest
- Stroke/Cerebrovascular accident
- Tachycardia
- Acute Coronary Syndrome
- Pancreatitis
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