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Slide Notes

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AUREA Nebula

Published on Nov 27, 2015

Aurea nebula

PRESENTATION OUTLINE

AUREA Nebula

Biological Network Analysis in the Cloud
Photo by emiliokuffer

Going Beyond Differential ExPression

  • DiRaC
  • At cloud scale
Photo by Steve took it

Untitled Slide

Architecture

How Fast

  • 1 GPU = 1000 CPU
  • 100,000 permutations
Photo by whlteXbread

HOw eXPensive

  • Used to cost $1500
  • Current results cost around $30
Photo by kenteegardin

Spot Price

Adapts to Pricing

How Useful

Track Network Changes over time with Empirical p-values

CurrentLy Run A Dozen times

  • 4 network sources (Biocarta, Kegg, GO, Reactome)
  • Adding new network sources is trivial
  • Comparisons are over k=11( k-nearest by age)
  • Next week Jocelynn will present

Current test

  • Generate rank template from k-nearest neighbors(age) in both sets 
  • Classify
  • Permute
  • Generating pvalues over accuracy for different time ranges
Photo by Xraijs_

How Easy

Demo

In Progress

  • Javascript APIs
  • Data Visualization
  • Aggregation improvements
Photo by luc legay

NoodLing

  • Bootstrap
  • Data Mining
  • Synapse
Photo by Tau Zero

DIRac Adaptations

  • Crosstalk Matrices
  • Multi-omic
  • Multi-class
  • Rank Difference
Photo by Microbe World