CANAVAN DISEASE

CHROMESOME

• Canavan disease affects the 17 chromosome it doesn't affect the 23
• It adds another 17th chromosome
• The leukodystrophy (When nerve cells break down)

SIGNS AND SYPTOMS

• Signs normally appear 3-9 months of life
• Some symptoms are bigger head circumference, lack of head control, reduced vision response, children with the disease cannot walk crawl or sit.
• You can not see symptoms at birth only from 3-5 months.

Untitled Slide

• this is a photo of the symptom. Larger head circumference

DISORDER

• The genetic disorder normally occurs in jewish heritage

LIFE EXPECTANCY

• Most infants only survive to the age of 10.

LIFE EXPECTANCY

• If you have a mild case of this disease you live to the age of 9-10
• If you have an aggressive case you are lucky to live pass the age of 4.

CHALLENGES

• They cannot walk, crawl or sit.
• Their parents have trouble feeding them.
• They have trouble talking.

TREATMENTS

• They can diagnose the disease by using multiple test.
• The test that they use are Cat scan, mri.
• These test are use to see the decline of white matter in the brain.
• They can also use blood test.

TREATMENTS

• There is no cure for canavan disease.
• There are no Therapies and No medications for the disease.

POSSIBLE TREATMENTS

• There are future treatments.
• So far they are doing gene replacement on mice.

THE WEBSITES WE USED

• Canavan disease.org
• canavanfoundation.org/research
• ulf.org/canavan-disease
• medicinenet.com/canavan_disease
• http://canavanfoundation.org/the_cause_of_canavan_disease
• http://www.nytimes.com/health/guides/disease/canavan-disease/overview.html