Canavan Disease

• history of the Canavan disease
• Named after Mrytle Canavan
• best known for the best description of the canavan disease
• also the first female pathologists
• in 1933 Dr. Rueban discovered the gene that causes the disease in tissue

example of the brain cells of the disease

Recent reseacch

• they have recently concluded that the Canavan disease acts as a sheath that forms around each nerve cell
• making clear transmission for nerve impulses

Facts

• Canavan as most deaths occur before the age of 4 some them have very slim odds of making it into their teens
• most of the time the effects are brain astophy ,loss of motor function ,seizures,blindness,hearing loss, large head,abnormal muscle tone ,and poorly controlled head
• and as in said before there is no cure for this disease

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• Canavan disease is the most common diseaseas far as ceberal-degerative diseases go
• a birth disorder linked by a gene in which the white matter of the brain deteriates into spongy tissue
• riddled w/ microscopic fluid filled spaces
• basiclly a they are genetic disorders known as ''luekodystrophies''
• causes the brain mostly atrophy
• terminally fatal!!!!

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• mutations in the ASPA gene may cause ,an enzyme to break down compound called ''n'' -acetyl -l asportic acid
• which is Perdominantly found in the cells of the brain

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