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Cannabis Hyperemesis
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Published on Dec 10, 2018
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PRESENTATION OUTLINE
1.
Hurling While High
Ian Mitchell, MD, FRCP
Photo by
Cannabis Culture
2.
Untitled Slide
Emergency Physician RIH
Clinical Associate Professor, Dept of EM
Site Scholar, Kamloops Family Medicine Residency Program
3.
Cannabis
QI for RCT of cannabis for PTSD- UBCO
Provider- MCRCI
Editor/Contributor - Using Medical Cannabis/Tilray
Senate Report on Cannabis
Photo by
floresyplantas.net
4.
Disclosures
Speaking fees: Tilray, Maricann
Consulting: Tilray, Shoppers Drug Mart, MD Briefcase
Investments: SDM
Photo by
Rick Proctor
5.
Allen,2004, Adelaide
?Moore, 1996, Sydney
Photo by
Sarah L Wilhelm
6.
CHS patients
male
prolonged cannabis use
abdominal pain
scromiting
hot showers/baths give relief
Photo by
Mike Burns
7.
Untitled Slide
Investigations negative
$25 000/year costs
Cessation only cure
Challenge causes return of symptoms
Photo by
Steve E.
8.
CHS vs CVS
CVS more in women
Heat cure rare in CVS
CVS begins in childhood
mitochondrial DNA ?
Photo by
Jenn and Tony Bot
9.
Etiology
THC decreases temperature
Cannabinoid receptors in hippocampus and gut
Photo by
svennevenn
10.
TRPV
pain (capsaicin)
triggered by high temperatures
Photo by
naotoj
11.
Jamaica
Photo by
PoshMoggy
12.
Neem Oil Hypothesis
unapproved pesticide
toxicity leads to vomiting
no CHS from edibles
sporadic distribution of CHS
Photo by
sk_vel
13.
Neem Oil Hypothesis
toxicity doesn't include hot showers
CHS seen with synthetic cannabinoids
Photo by
{ pranav }
14.
Treatment
Rehydration
Antiemetics
Benzodiazepines
Photo by
Laurel L. Russwurm
15.
Haloperidol 5 mg im/iv
Olanzapine 5 mg iv
Olanzapine has less EPS and less cardiac side effects than haloperidol, but is more expensive.
16.
Capsaicin
0.075% to abdomen / back of arms
Photo by
dark.Reactions
17.
How Long?
4-10 days ?
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nisuspi
18.
Recidivism
?Benzodiazepines for withdrawal
Photo by
Dan4th
19.
Legalization
Doubling of cases in Colorado
20.
Stigma
LWBS 20%
Photo by
nikoretro
21.
CHS:Public Health Implications and a Novel Treatment Guideline, LaPoint, et al, 2017, West J E M
Photo by
Sarah Cervantes
22.
Questions?
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sobriquet.net
Ian Mitchell
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