HEPARIN

Heparin

• Generic name = Heparin sodium
• Trade name = Hep-lock, Calciparine

Administration Route

• Subcutaneous
• IV bolus
• IV drip

Drug Source

• Derived from mucosal tissue of animals such as pig or cow.

Manufacturer

• Baxter Healthcare Corporation is the leading manufacturer

Warnings/Precautions

• Safely administered in correct doses
• Too much can lead to internal bleeding, hemorrhage, or death

Drug Classification

• Anticoagulant
• Prevent or interfere with blood coagulation

Strengths and Forms

• May come in a Single-Use Vial of 1,000 units/ML, 5,000 units/ML or 10,000 units/ML
• Also available in Hep-Lock Flush of 10 units/ML or 100 units/ML

Common Side Effects

• Bleeding, itching and burning

Adverse Effects

• Hemorrhage and Thrombocytopenia (decrease in platelets)
• Allergic or hypersensitivity reactions

Administration

• Heparin is administered by the anesthesia provider 3 minutes prior to the procedure
• This allows it to work into the system before the first incision is made

Surgical Procedures

• Most commonly used in peripheral and cardiovascular procedures
• May be used in vascular procedures such as a femoral embolectomy

Heparin

• Can be given to pregnant patients because it does not cross the placenta
• 5 minute onset/2-4 hours
• Not to be used on patients with severe thrombocytopenia
• Antidote is protamine sulfate

Reference

• Snyder, Katherine C. Pharmacology for the Surgical Technologist. Pp. 149 - 151.