AND THE IMPACT OF MUTATION

THE PROCESS BY WHICH A POLYPEPTIDE CHAIN ASSUMES ITS 3D FORM

IN THE ABILITY TO FOLD IS THE THERMODYNAMICS OF THE STRUCTURE

MAIN STABILIZING FORCE IN A PROTEIN

HYDROPHOBIC REACTIONS WITHIN THE PROTEIN

DISULFIDE LINKAGES THAT FORM WITHIN THE PROTEIN

WHEN A PROTEIN IS MIS-FOLDED, IT CAN LEAD TO DENATURATION

LOSS OF PROTEIN STRUCTURE AND FUNCTION

CAN SOMETIMES LEAD TO DISEASES. EX: ALZHEIMER'S DISEASE OR CYSTIC FIBROSIS