PROGERIA

WHAT IS PROGERIA?

• Progeria is a genetic mutation that can cause children to age very fast.
• Most of the children with the disease die by the age of 13.

GENES

• The gene that causes this is called LMNA
• The normal LMNA produces the protein lamin A protein which is the structural scaffolding that holds the nucleus of w cell together. The abnormal LMNA messes up the scaffolding, which results in an unstable nucleus in the cell.

SYMPTOMS

• Slow development
• Hair loss
• Wrinkles on the skin
• Enlarged head
• Physical deformity

GOOD/BAD

• This disease is 99% bad!
• There is really nothing in the disease that is good.
• The only good that comes out of it is that the doctors can do more research and human clinical trials on them.

Untitled Slide

• In the picture the top right is of the normal human and the bottom is of a person with progeria.

CITATIONS

• "10 Unusual Genetic Mutations in Humans." Io9. N.p., n.d. Web. 26 Oct. 2015. .