Immune System
Published on Nov 19, 2015
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PRESENTATION OUTLINE
FUNCTION: To protect the body from infectious microorganisms
MAJOR ORGANS
- Bone marrow
- Thymus
- Spleen
- Lymph nodes
- Liver
- Skin
- Adenoids
PATHOGENS
- Antibodies recognize antigens
- Antigens are unique proteins on every pathogen
INNATE IMMUNITY
- From birth
- Non-specific
- Mechanical barriers
- Antibacterial secretions
ACQUIRED IMMUNITY
- Pathogen specific
- Immune response
- Immunological memory
- The flu, chicken pox
ACTIVE IMMUNITY
- Induced immunity
- Vaccine
- Infection
PASSIVE IMMUNITY
- Induced immunity
- Transferred serum
- Transferred lymphocytes
- From immune person
HUMORAL RESPONSE
- Antibody mediated
- B cells proliferate and produce plasma cells
- Plasma cells make antibodies
- B cells produce memory cells
CELL-MEDIATED
- T-cells recognize aberrant cells
- Cytotoxic T-cells destroy cells with the antigen
- Helper T-cells may proliferate
- B-cells may summon macrophages
- Less specific
B-CELLS
- Mature in bone marrow
- Don't kill viruses themselves
- Become plasma cells
- Release antibodies
T-CELLS
- Mature in the thymus
- Covered in TCRs
- Killer T-cells release cytotoxin
- Helper T-cells release hormones to coordinate immune response
ANTIBIOTICS
- Block bacterial metabolic processes
- Viruses don't do their own metabolic processes
HIV/AIDS
- Virus that attacks immune system
- Difficult swallowing
- Sores and ulcers
PREVALENCE AND TREATMENT
- In 2013, 35 million were living with AIDS
- No cure
- Drug cocktails
ASTHMA
- Over 3 million cases per year
- Wheezing, chest tightness
- Coughing at night or in the morning
PREVALENCE AND TREATMENT
- Over 20 million cases of asthma
- No cure
- Use of inhalers
