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Kuru

Published on Nov 29, 2015

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PRESENTATION OUTLINE

TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES (TSES)

NEURODEGENERATIVE PRION PROTEIN BY: JESSE HAZELTON 5TH HOUR

LOCATION

LOCATION OF THE KURU PROTIEN

NEW GUINEA

THE HISTORY OF KURU

  • It was first found in the villages of New Guinea
  • It spread because of endo-cannibalism (eating of dead relatives)
  • Kuru affects the brain by slowly eating it away

CAUSES

  • Eating of an infected brain by cannibalism

More causes-
The kuru prion protein kills neurons in the brain and leave the brain full of holes.

INCIDENCE

  • It affected women and children the most
  • It affect everyone that eats the infected brain
  • It has a 5-20 year incubation period and once you show symptoms you will die within a year

DIAGNOSIS

  • blood test
  • Folic acid level test
  • Liver/kidney test
  • MRI
  • Electromyography

SIGNS/SYMPTOMS

  • Arm and leg pain
  • Headache
  • Tremors and muscles spasms
  • Difficulty walking
  • Coordination problems that become severe
  • Swallowing difficulty
  • Random laughing or crying
  • Slurred speech
  • Moodiness

PATHOLOGY

  • mainly affects the cerebellum (controls coordination)
  • they died in a comatose state - 6 to 12 months after the first appearance of symptoms.
  • To get Kuru you just need to eat an infected brain
  • The kuru protein eats at the cerebellum and it will slowly kill you

TREATMENT

  • There is no cure
  • The only way to not get it is to not eat an infected brain
  • No treatment
  • Kuru is always fatal

Prevention-
The only way to prevent this disease is by not eating an infected brain

ADDITIONAL INFOMATION

  • Kuru was discover in New Guinea in the 1950s
  • Kuru is related to Mad cow disease and scrapie(like the kuru disease but affects sheep and goats)
  • The Fore tribe of Papua New Guinea ate every part of their deceased including their bones and feces. This practice known as endo-cannibalism, was actually born out of love and respect as they viewed it as a way their deceased to literally live on forever.