PRESENTATION OUTLINE
OBJECTIVE
Discuss therapeutic hypothermia as implemented by ACCESS agencies
ROSC
(Return Of Spontaneous Circulation)
a. ROSC
i. Per AHA “It is recommended that comatose adult patients with ROSC after out of hospital VF-associated cardiac arrest be cooled… (Class I, LOE B).”
ii. Per AHA “Therapeutic hypothermia may be considered… after out of hospital cardiac arrest with an initial rhythm of PEA or asystole (Class IIb, LOE B).”
iii. While intra-arrest cooling studies in animal models show some promise, human studies are underway but have not yet been published.
Age > 16 years
b. Age > 16
i. Studies have only been done in adult patients.
Temp > 34C/93.2F
c. Temp > 34C/93.2F
i. Target temperature per AHA recommendation is 32-34C.
SBP > 90 mmHg
d. SBP > 90 mmHg
i. Physician “Pearl”: SBP >90 needed before initiation of cooling. Patients may require vasopressors to meet this inclusion criteria.
1. Dopamine infusion
a. IV: 5-20 mcg/kg/min
2. Epinephrine infusion
a. IV: 2-10 mcg/min
b. … appears to not require medical control in this case
Comatose
e. Neuro exam 5 min post-ROSC shows no purposeful pain response
i. AHA recommends “comatose” patients.
POST/DNR
a. DNR/POST, or other advance directive
i. Naturally.
Obvious Terminal Illness
b. Obvious Terminal Illness
i. You’d think they would have a POST/DNR.
ii. Kind of a judgement call.
Obvious Pregnancy
c. Obvious Pregnancy
i. Literature shows this as a “relative contraindication”…
Obvious Traumatic Arrest
d. Obvious Traumatic Arrest
i. He’s got bigger problems.
If the patient isn't intubated, and you elect to induce hypotermia...
Ventilate to ETCO2
of 35 mmHg
IV/IO/IM:
0.5-2.5 mg slow IV push every 5-10 minutes (max dose 5 mg)
IN:
2.5 mg every 10 min (max dose 5 mg)
Only when patient intubated and placement confirmed with SpO2 and ETCO2
IV/IO:
0.1 mg/kg repeated PRN
If vecuronium is administered, ensure midazolam is provided for patient sedation.
Establish a 2nd IV if possible
i. Establish a 2nd IV if possible
1. This may be left over from when we used chilled crystalloid.
2. Can’t hurt, though.
(The patient's groin, axilla and neck.)