SICKLE DISEASE

DR. JAMES B. HERRICK

CURRENT RESEARCH

• In 2009, scientists discovered that a modified transplant of adult blood stem .
• cells couldyse in 9 of 10 adults who had been severely affected by the disease
• In 2010, a study found that neurologically normal adults with sickle cell disease scored lower on tests
• of brain function than neurologically normal adult participants who did not have sickle cell disease

SYMPTOMS/SIGNS

• Severe pain Anemia Chest pain and difficulty breathing Strokes Joint pain and arthritis and bone infarctions Blockage of blood flow in the spleen or liver Severe infections
• The signs are fevers and it sometimes around the neck

AFFECTS TO BODY

• blood and various organs in the body
• red blood cells
• Oxygen is affected
• liver, kidney's, heart, brain, lungs,and the joints

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• Sickle cell disease is an inherited condition.
• . Two genes for the sickle hemoglobin must be inherited from one's parents in order to have the disease
• Not sexlinked
• The disease is caused by a mutated version of the gene

TREATMENTS

• over-the-counter pain medicines, heating pads, rest, and plenty of fluids
• treated with a medicine called hydroxyurea
• Blood transfusions

DIAGNOSED

• Doctors also can diagnose sickle cell disease before birth.
• This is done using a sample of amniotic fluid or tissue taken from the placenta.

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