The infection can spread through the bloodstream and travel to the bone or it can start in the bone itself if the bone is exposed to bacteria from a wound
In children, Osteomyelitis mostly affects the long bones in the arms and legs. In adults it affects the spine and people with diabetes it can affect their feet if they have foot ulcers .
Recent injury or orthopedic surgery: A severe bone fracture or a deep puncture wound gives infections a route to enter your bone or nearby tissue. Surgery to repair broken bones or replace worn joints also can accidentally open a path for germs to enter a bone.
Conditions that impair the immune system: Chemotherapy,Poorly controlled diabetes,
Needing to take corticosteroids or drugs called tumor necrosis factor (TNF) inhibitors
Illicit drugs: People who inject illicit drugs are more likely to develop osteomyelitis because they typically use nonsterile needles and don't sterilize their skin before injections.
A bone biopsy will reveal what type of germ is causing your infection, so your doctor can choose an antibiotic that works particularly well for that type of infection. The antibiotics are usually administered through a vein in your arm for at least four to six weeks.