“We shall not cease from exploration, and the end of all our exploring will be to arrive where we started and know the place for the first time.” -- T.S. Eliot
The journey from matter to mind and back again is the ultimate in self-reflexivity.
For example, we can follow a path or a hierarchical arrangement leading full circle from: 1) the quantum realm, 2) microtubules, 3) neurons, 4) neuronal cluster, 5) brain tissue, 6) brain region, and finally 7) consciousness, which twists back, as it were, seeking its quantum roots.