This was unethical in that, it injected unsuspecting patients with a harmful element, to see how they would react. The researchers then lied saying that the patients were terminally ill, yet they were all in fact , in perfect health.
The main character in Deadpool (wade Wilson) was tricked into a human experimentation project to create mutants. He was put through various tests and tortured in order to mutate his DNA this added stress and torture eventually did cause him to mutate yet it left him with disgusting side effects causing him to have to hide his face for fear of being shunned due to his ugly complexion