DUANE SYNDROME

INTRODUCTION

• Duane Syndrome
• By Zach McKaughan
• Ryan Claybourn,
• & Suzanne.

DEFINITION

• It contracts the eye muscles involuntarily
• Eye muscles

SYMPTOMS

• Eye muscles involuntarily contract.
• Eye muscles do not contract when they are suppose to.
• Affected eye may abduct slightly back into the socket
• Poor convergence

CAUSES

• The contractions are caused by miswired eye muscles
• Abducens nucleus or nerve are missing
• Nerves miswired cause inverted muscles
• It is a mutation in the CHN1 gene

INHERITENCE

• It might be both environmental and genetic
• Cases showing genetic origin have both dominant
• and recessive forms of Duane Syndrome.
• It is not sex linked and it shown in both men and women
• It is shown on the CHN1 gene

TREaTMENT

• Un curable
• It can be treated with occlusion
• Surgery can be used to attempt to
• centralize the eye.
• There are no medications

DIAGNOSES

• Done early childhood;
• patients are tested for abduction limitations
• Child is asked to turn head during examination

DISORDER STATISTICS

• 60% of cases are in females
• 40% of cases are in males
• It is a very rare syndrome having as few as
• 54 cases per year; and is less than 0.01%

APPLICATION

• We learned that this disorder happens more in females than males
• That it happens more commonly in girls than boys
• That it has an extremely rare amount of cases