PROGERIA

What is Progeria?

A congenital genetic disease that causes premature aging, can affect anyone

SYMPTOMS OF PROGERIA

• Baldness
• Aged appearance
• Macrocephaly
• Short stature
• Symptoms related to old age

DAILY LIFE

• Mostly the same as normal children
• Physical therapy
• Custom clothing
• Home modification
• Travel changes

What is the life expectancy of someone with Progeria?

13 years average

What mutation cause Progeria?

A point mutation in LMNA.

What chromosome is affected?

Chromosome 1

What is the name of the gene that is mutated?

LMNA, codes for two proteins: lamin A and lamin C

The meaning of Progeria

"geras" is the Greek word for old age

What are the possible treatments?

Medication: Lonafarib

Is there a cure for Progeria?

No

Interesting Information

The oldest person to live with Progeria died at 26 years old,
1 in 4-8 million newborns are born with Progeria

Bibliography

7., 1., Living, With, and Proger Ia. 17. Living with Progeria (n.d.): n. pag. Web.
"Learning About Progeria." Learning About Progeria. N.p., n.d. Web. 26 Oct. 2014.
"Life According To Sam Berns." Life According To Sam Berns. N.p., n.d. Web. 26 Oct. 2014.
"My Progeria Project." My Progeria Project. N.p., n.d. Web. 26 Oct. 2014.
"WE DID IT! First-ever Treatment for Progeria Discovered!!" Progeria Research Foundation. N.p., n.d. Web. 26 Oct. 2014.