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Gene To Protein

Published on Nov 19, 2015

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PRESENTATION OUTLINE

GENE TO PROTEIN

CATHERINE MOXLEY

DNA FROM GENES ON CHROMOSOMES RUN RNA PROCESSING

Photo by Image Editor

rRNA CONTROLS PROTEIN SYNTHESIS

PROTEIN SYNTHESIS STARTS WITH TRANSCRIPTION

RIBOSE SUGAR IS THE BUILDING BLOCK OF RNA

DNA CHANGES TO A SINGLE STRAND AND IS NOW A TRANSCRIPTION UNIT

RNA POLYMERASE IS AN ENZYME WHICH PERFORMS TRANSCRIPTION

TRANSCRIPTION FACTORS ATTACH TO PROMOTERS

DNA STRANDS ARE PULLED APART

DOUBLE HELIX UNWINDS

DNA WINDS AROUND HISTONE PROTEINS

RNA POLYMERASE PAIRS UP NUCLEOTIDES AND COMPLEMENTS

THE TEMPLATE STRAND IS USED FOR RNA SYNTHESIS

THE CODING STRAND IS USED TO SIGNAL THE TATA BOX

POLYMERASE CODES FOR CODONS

POLYMERASE MOVES FROM 3' TO 5' ADDING NUCLEOTIDES

URACIL PAIRS WITH ADENINE

THYMINE, GUANINE AND CYTOSINE ARE ALSO N- BASES

RNA PROCESSING HAPPENS BEFORE TRANSCRIPT IN EUKARYOTIC CELLS

PRIMARY TRANSCRIPT DOES NOT CODE FOR A POLYPEPTIDE

A CODING SEGMENT IS A POLYPEPTIDE WITH A START CODON AND A STOP CODON

A CAP OF GUANINE IS ADDED TO THE 5' END

THE 3' END HAS A POLYA TAIL OF ADENINE

SPLICEOSOMES FORM MORE PROTEIN STRUCTURES

INTRONS ARE DELETED

EXONS ARE CONNECTED

MRNA IS FINISHED

RNA LEAVE THE NUCLEUS AND ENTERS THE CYTOPLASM

PROTEIN IS TRANSLATED FROM RNA

TRANSLATION FORMS A POLYPEPTIDE CHAIN

MRNA GOES THROUGH A RIBOSOME

AMINO ACIDS MAKE UP POLYPEPTIDES

TRANSFER RNA PAIRS BASES WITH AMINO ACIDS

INITIATION, ELONGATION, AND TERMINATION TAKE PLACE

AN ANTICODON BONDS TO THE START CODON AUG

METHIONINE IS GIVEN BY TRNA

AN INITIATION COMPLEX IS FORMED

ELONGATION NOW OCCURS

CODINS PAIR WITH ANTICODONS TO LENGTHEN THE POLYPEPTIDE

THE PEPTIDE BOND IS CATALYZED

STOP CODONS END TRANSLATION

RELEASE FACTORS BIND STOP CODONS

THE TRANSLATION ENDS

POLYPEPTIDES ARE ALTERED WITH OTHERS TO FORM A NEW PROTEIN