PARKINSON'S DISEASE

WHAT PARTS ARE AFFECTED

• Neurons in the substantia nigra
• Basal Ganglia

WHERE DID IT GET ITS NAME

• Dr James Parkinson
• Described as "shaking palsy"
• Also known as Parkinsonism

WHAT IS DIFFERENT IN THE NERVOUS SYSTEM

• Dopaminergic neurons
• Lewy bodies
• Lighter substantia nigra
• Can't carry out actions

WHAT CAUSES IT AND HOW IS IT CLASSIFIED

• Genetic or environmental
• Degenerative
• Not preventable

WHO IS MOST LIKELY AFFECTED BY IT

• Late fifties and sixties
• Caucasians
• Average age of 59

PROGNOSIS

• Life-long
• Worsens over time
• Is life-threatening
• Will not be able to control with drugs or treatment
• Final symptoms of hallucinations and dementia

TREATMENT AND HOW IT AFFECTS THE PATIENT

• Levadopa and selegiline
• Treatment helps for first 5-10 years
• Exercise, nutrition, and physical therapy
• Surgery
• No cure

DIAGNOSIS

• Look at symptoms
• Test to check for diseases with similar symptoms
• Can be diagnosed when already dead

SYMPTOMS

• Tremor
• Altered Posture
• Slowness of Movement
• Muscle rigidity
• Etc.

FREQUENCY AND OCCURANCE

• Over 1,000,000 cases in US
• Average of 60,000 more cases every year

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