EPIDERMOLYSIS BULLOSA

CAUSES

• Genetic mutation
• Inhibits production of certain proteins
• Or proteins are formed incorrectly
• Hereditary

SYMPTOMS

• Severe blistering of the skin
• Deformity/loss of toenails and fingernails
• Blisters in the mouth/ lining of throat, mucous membranes
• Dental abnormalities
• Thin skin

PROGNOSIS

• Sometimes lethal
• Will usually affect lifestyle
• Extremely painful
• Chronic malnutrition & stunted growth

TREATMENT

• Puncture blisters to prevent spreading
• Antibiotics and bandages
• Prevent infection
• Surgery & Gastronomy tube
• Physical therapy

SIMPLEX

• Blisters on hands and feet
• Minimal scarring
• Keratin producing genes
• Inherited from one parent

JUNCTIONAL

• Epidermis separates from the dermis
• Hemidesmosome producing genes
• Inherited from both parents

DYSTROPHIC

• Collagen producing genes
• Fibers holding deepest layers of skin together
• Missing or dysfunctional

RESOURCES

• http://www.mayoclinic.com/health/epidermolysis-bullosa/DS01015
• http://allaboutepidermolysisbullosa.blogspot.com