Progeria
Published on Nov 18, 2015
No Description
MORE DECKS TO EXPLORE
PRESENTATION OUTLINE
ABOUT
- Pro- before
- Geria- old age
- 1 out of every 8 million people are born with progeria
- Life span is 15-20 years
- Age insanely fast
Photo by ˙Cаvin 〄
SYMPTOMS
- Failure to thrive
- Localized skin conditions; similar to scabs; they eventually reach organs
- Limited growth
- Very wide forehand; very underdeveloped jaw
- Loss of eyesight, hair loss, cardiovascular problems, easily broken bodies; still maintain regular motor development
Photo by Vox Efx
CAUSE
- Mutation on the LMNA gene; in which cytosine is replaced with thymine
- Causes transcription to occur to quickly--therefor creating an abnormally short LMNA transcript
- An abnormal protein is formed called progerian
- Progerian does not support the nuclear envelope, causing dis functional cellular division
- Makes one's life less than desirable
Photo by travisbell
DIAGNOSIS AND TREATMENT
- Diagnosed by checking for LMNA gene mutations
- There are no treatments
- Although there is no cure, multiple cancer drugs are used to stop proliferation in dysfunctional proteins
- People with Progeria die at a young age
Photo by Instant Vantage
