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Smallpox by: Luke Lively

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PRESENTATION OUTLINE

SMALL POX

BY: LUKE LIVELY

Smallpox is caused by the variola virus that emerged in human populations thousands of years ago. Except for laboratory stockpiles, the variola virus has been eliminated.

The Variola virus is a double-stranded DNA virus. It has two envelopes: the outer envelope is present only in the extracellular state. The outer surface or the core membrane, which surrounds the core of the virus, contains lipids and proteins and has a complex symmetry.

The first symptoms of smallpox include fever, malaise, head and body aches, and sometimes vomiting.

There is no proven treatment for smallpox disease. Prevention is achieved through vaccination.

HOW IT SPREADS

  • By blood products (unclean needles or unscreened blood).
  • By saliva (kissing or shared drinks).
  • By skin-to-skin contact (handshakes or hugs).
  • By airborne respiratory droplets (coughs or sneezes).

In addition to flu-like symptoms, patients also experience a rash that appear first on the face, hands and forearms, and then later appears on the entire body

The diagnosis of smallpox is made in specialized laboratories with appropriate testing techniques and measures to protect the laboratory workers.

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LIFE CYCLE OF SMALL POX

  • Virus attack to the cell and get into the cell.
  • Variola virus will share their RNA to the cell, so the cell infects with virus.
  • Virus will mix with nucleic acids and proteins from the cell.
  • Virus will reproduce themselves inside a cell.
  • After virus gets reproduced, they will break the cell wall of the cell and come out, that kills the cell immediately .

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