THYROXINE & TRIIODOTHYRINE

PRODUCTION

• 20% is produced by the thyroid gland
• The other 80% is produced and converted by the kidneys and liver.
• The kidneys and liver activate the hormone

SECRETION

• controlled by a negative feedback system.
• Lack of thyroid hormones result in higher levels of TSH
• TSH(thyroid-stimulating hormone)
• Excess of thyroid hormones result in lower levels of TSH

FUNCTIONS

• As a thyroid hormone it helps control many things
• Metabolism (weight gain & weight loss)
• Heartrate
• Digestive functions
• Body temperature and muscle control.

GRAVE'S DISEASE

• Caused by hyperthyroidism.
• Symptoms include
• Heat intolerance, weight loss, irregular heartbeat
• tiredness, tremor, hair loss
• And retraction of the eyelids to create a staring appearance.

Untitled Slide