T X SYNDROME

DEFINITION

• the presence of an extra X chromosome
• only occurs in females
• when there are 3 X chromosomes instead of 2
• can causes developmental delay or learning disabilities
• chromosome doesn't appear until early

SYMPTOMS

• vertical skinfolds that may cover inner corners
• curved pinky fingers
• delayed development in speech
• weak muscle tone

CAUSE OF DISORDER

• is not inherited
• chromosomal change occurs at random
• it is an error in cell division called nondisjunction
• a mutation
• but is not triggered by other factors

HOW IS IT INHERITED?

• it is not sex-linked but can be a gamete mutation
• it is located on the X chromosome
• it is recessive

HOW IS IT TREATED?

• if it causes a disability counseling is recommended
• otherwise it is not treatable
• gene therapy is an option

HOW IS IT DIAGNOSED?

• prenatal: amniocentesis testing or sampling
• after-birth: analysis on blood sample
• genetic counseling is an option

HOW MANY PEOPLE?

• it is common in only females
• there is 1 in every 1,000 newborn females

NEW INFORMATION?

• can not tell who has the disorder
• does not physically change a person
• infertility is possible but not common